Hepatocellular carcinoma (HCC) is a common malignancy and a leading cause of cancer-related mortality. Current guidelines and staging systems provide coarse categories, but often miss within-stage heterogeneity and the clinical context in electronic medical records (EMRs). We present HCC-STAR (Hepatocellular Carcinoma Staging, Treatment And pRognosis), a clinically aligned large language model that reads routine EMR narratives and jointly outputs risk score-based staging, ranked guideline-consistent treatments with evidence-based rationales, and individualized survival estimates. We curated about 30,000 HCC cases from SEER and expanded them into EMR-style narrative training data using a clinician-validated, prompt-based augmentation workflow. On this corpus, we developed a knowledge-aligned reasoning framework optimized with a step-verifiable composite reward, moving beyond text-level memorization of clinical guidelines. In a multi-center cohort of 6,668 patients from 12 hospitals in China, HCC-STAR achieved state-of-the-art performance in treatment recommendation and risk stratification compared with clinical guidelines and competitive models, including GPT-5 and Gemini-2.5 Pro. Hypothetical overall-survival analysis showed a median survival of 51 months under adherence to HCC-STAR recommendations, compared with 29 and 32 months under BCLC and CNLC. In clinician-centric evaluations, blinded hepatobiliary specialists rated HCC-STAR's reasoning and evidence-based justifications as trustworthy. The model surpassed resident and attending physicians in treatment accuracy and helped physicians make more accurate decisions faster when used as an assistant. These findings support HCC-STAR as a reliable and verifiable decision-support system for risk stratification and precision therapy in HCC.
Sparsely-activated Mixture-of-Experts (MoE) language models achieve remarkable inference efficiency by activating only a small fraction of parameters per token, yet their full expert banks reside in memory at all times, creating a prohibitive deployment bottleneck. Existing structured pruning methods, largely designed for dense transformers, assess expert importance using locally derived heuristics that are blind to the interdependent nature of MoE routing. We introduce MAESTRO (Markov-chain Approximated Expert Sparsification via Transition-based ROuting), a structured pruning framework designed for MoE architectures that models autoregressive expert activation trajectories as Ergodic Markov chains whose stationary distributions encode cross-layer dependencies, yielding a globally aware importance heuristic. Evaluated across five diverse domains including Safety, Bias, and Ethics, MAESTRO outperforms state-of-the-art baselines by up to 10.61% in average performance retention under a strict 50% compression regime, while exhibiting substantially lower cross-task variance, indicating that global, routing-congruent pruning produces models that generalize more consistently across heterogeneous tasks.
Multimodal emotion and sentiment recognition is commonly addressed by early fusion, which concatenates modalities before classification, or late fusion, which combines independently trained unimodal predictors. Early fusion can be accurate but monolithic, while late fusion is modular but may lose cross-modal interactions. This paper revisits XAI-guided adaptive fusion (\xgaf), a tree-based mixture of unimodal and cross-modal experts whose sample-level weights are derived from TreeSHAP attribution magnitudes. We focus on the effect of SHAP attribution reduction when experts have unequal feature dimensionalities. In this setting, mean-abs and median-abs reductions can suppress high-dimensional cross-modal experts, whereas sum-abs reduction preserves total attribution mass. On MELD 7-class emotion recognition, sum-abs \xgaf{} nearly matches early fusion across three face-sequence aggregators; the Transformer variant reaches 0.5983 \wf{}, compared with 0.6018 for early fusion and 0.4598 for probability-average late fusion. McNemar testing shows no significant difference between sum-abs \xgaf{} and early fusion on MELD ($p=1.000$), while \xgaf{} remains significantly better than late fusion ($p<0.0001$). On CMU-MOSEI 3-class sentiment recognition, sum-abs \xgaf{} reaches 0.6519 \wf{}, slightly exceeding early fusion (0.6485) and late fusion (0.5696). Ablation studies show that the main gain comes from adding cross-modal experts, especially the trimodal expert, rather than from complex per-sample routing. Diagnostics further show that mean-abs and median-abs weights are nearly uniform, while sum-abs weights concentrate on the trimodal expert. Thus, the main contribution is a transparent empirical analysis of how SHAP reduction, expert dimensionality, and cross-modal expert design affect modular multimodal fusion.
Multimodal Large Language Models (MLLMs) often follow a fixed Think-then-Answer paradigm, which is inefficient in heterogeneous multitask settings because simple inputs may not require explicit reasoning while difficult ones can benefit substantially from it. Learning when to think is also unstable during post-training, where imbalanced rollouts can drive the model toward always-thinking or always-direct behavior. We propose Switch-Reasoner, a GRPO-based framework that learns to adaptively select reasoning modes for MLLMs. It treats thinking as a virtual tool invocation and allows the model to either answer directly or invoke explicit reasoning before answering. To stabilize this decision, we introduce a dual-level regulation mechanism that balances the overall use of Thinking Mode and Direct Mode while providing sample-level supervision based on the relative benefit of the two choices. Experiments on 11 multimodal tasks show that Switch-Reasoner reduces unnecessary reasoning while maintaining strong performance, achieving a better accuracy-efficiency trade-off.
LLM scheduling is critical to serving, yet it remains unclear how well existing designs fit agentic serving--with LLM requests issued by agents instead of humans. This shifts the workload in two ways: (1) agents act only on complete responses, making the cluster's tokens per second (TPS) the primary goal and relaxing--not eliminating--per-token latency requirements; and (2) requests share much of their KV\$-reuse exceeds 80% of request tokens in a production trace from BAILIAN, versus 54-62% in chat. This paper first contributes a systematic study of request scheduling for agents on two real-world traces. We find that to increase KV\$ reuse, existing schedulers overly prioritize routing requests to instances caching their KV\$, overloading a few while leaving the rest idle, capping TPS. We thus present two key insights: (1) load balance need not sacrifice all KV\$ reuse, thanks to the global-tier KV\$ store and (2) by utilizing the workload's intra-session locality, balancing a small fraction of requests--the first request in each agent session--suffices to balance the cluster without sacrificing most KV\$ reuse on local instances. SMETRIC realizes these insights with balanced session-centric scheduling: it routes each session's first request purely for load balance and its follow-up requests in a cache-aware manner, preserving load balance and local reuse while keeping demand on the global tier low. Using the session turn information as the scheduling metric is deliberate: it is derived efficiently and accurately from the user inputs alone, so the scheduler stays clean and stateless. SMETRIC improves cluster TPS by 10-16% under prefill-decode colocation with a global store and prefill TPS by 2-34% under disaggregation over state-of-the-art schedulers, also with a better per-token latency.
For urban managers and designers, improving the functional attributes of urban communities to enhance territorial resilience in the face of complexity and uncertainty is crucial. Currently, community planning often follows a top-down approach and lacks effective metrics to quantify informal behaviors of residents, leading to frequent conflicts with original plans. This study introduces CommuniWave, a machine learning model designed to efficiently detect and quantify the Degree of Informal Behavior (DIB) in urban communities. The model integrates a Behavior Capture Net (BCN) based on mmaction2, a self-developed YOLOv10 model (YLX), and a Behavior Eval Model (BEM) using random forest. Ultimately, by generating DIB fluctuation charts from street videos, the model facilitates dynamic monitoring, supporting urban managers in making refined decisions to enhance the overall resilience of communities.