AI Research Papers

Computer Vision & Image Generation7/8/2026

MedPMC: A Systematic Framework for Scaling High-Fidelity Medical Multimodal Data for Foundation Models

Medicine is inherently multimodal, requiring clinicians to synthesize information across diverse data streams. Yet the development of multimodal foundation models is constrained by limited access to large-scale, high-quality clinical data. Although PubMed Central (PMC) offers a complementary source of expert-authored image-text data, existing PMC-derived resources remain limited in fidelity, reproducibility, and clinical validation. We introduce MedPMC, an automated, continuously updatable framework that transforms permissively licensed literature into high-fidelity infrastructure for medical multimodal models. Applied to 6.1 million PMC articles, MedPMC curated 11 million medical image-text pairs. Component evaluations showed strong performance for initial screening (F1 = 93.2), multi-panel figure detection (F1 = 96.5), figure separation (mAP = 89.8), caption separation and alignment (F1 = 81.4; ROUGE-L = 85.3), and medical figure classification (F1 = 96.5). Manual review by five annotators, three with medical training, found 95.3% of MedPMC images medically relevant, versus 19.7% in a prior PMC-derived dataset. Across 26 benchmarks spanning 11 specialties, a MedPMC-trained CLIP-style model improved average zero-shot AUC by 7.1 percentage points over the strongest architecture-matched biomedical CLIP baseline despite using fewer than half as many image-text pairs. As the vision encoder in a multimodal large language model, it improved medical visual question-answering by 1.9 and 16.9 percentage points across two benchmarks. In 10,524 Yale New Haven Health System dermatology photographs, it improved morphology-to-image retrieval Recall@5 by 11.7 percentage points. These findings show that high-fidelity literature curation strengthens medical multimodal foundation models across benchmark and clinical settings. We publicly release the framework, corpus, benchmarks, and pretrained models.

Computer Vision & Image Generation7/8/2026

AA-ViT: Anatomically Aware Vision Transformer with Structural and Frequency Guidance for Contrast Enhanced Brain MRI Synthesis

Accurate tumour localization and diagnosis is a critical component of clinical care for brain cancers. Magnetic Resonance Imaging (MRI) is the most commonly used imaging modality due to its superior soft-tissue contrast. However, standard MRI often exhibits limited contrast and imaging artifacts, which necessitates the use of contrast agents to enhance lesion visibility. The administration of chemical contrast agents is not always feasible and may be contraindicated in patients with renal impairment or other health conditions. As a result, developing accurate and non-invasive contrast enhanced MRI (CEMRI) synthesis methods has clinical importance. In recent years, numerous approaches for CEMRI synthesis have been proposed, predominantly relying on generative artificial intelligence models. While these methods demonstrate promising performance, their dependence on implicit feature learning often limits their ability to preserve anatomical boundaries and tumour-specific fine structures. To address these challenges, we propose an anatomically aware frequency-and-structure-guided vision transformer (AA-ViT), for CEMRI synthesis using pre-contrast MRI modalities (T1, T2, and FLAIR). Experiments on the BraTS 2021 dataset demonstrate that the proposed method preserves anatomical and lesion boundaries, achieving higher PSNR and SSIM than state-of-the-art approaches. Clinical evaluation by three neuroradiologists and a neurosurgeon on 19 randomly selected cases across diverse gliomas yielded a mean score of 3.94/5, providing preliminary clinical validation rarely seen in prior studies. Synthetic post-contrast scans from our model could lower scanning costs, shorten imaging time, and avoid the potential risks of using gadolinium-based contrast agents.

Computer Vision & Image Generation7/8/2026

Face-trace: Open-Set Attribution and Progressive Discovery of Synthetic Face Generators

Recent advances in generative Artificial Intelligence have made synthetic face images increasingly realistic, creating new challenges for multimedia forensics. Source attribution methods should not only identify the generator of an image when the source is known, but also handle samples produced by previously unseen models. However, most existing approaches address synthetic face attribution in a closed-set setting, where all possible generators are available during training. This assumption does not hold in real-world scenarios, where new generators continuously appear and rejected samples should be organized rather than simply discarded. In this work we propose a pipeline for open-set synthetic face source attribution that combines known generator classification, energy-based OOD rejection, and unknown generator discovery. A classifier is trained on known generators using frozen I-JEPA embeddings, while rejected samples are represented by combining projected I-JEPA features with Forensic Self-Descriptors and then clustered to discover groups of unknown generators. We also extend the discovery stage to an incremental scenario, where rejected samples arrive over time. Experiments on the WILD dataset show that the proposed method achieves 96.73% closed-set attribution accuracy. In the open-set setting, energy-based rejection reaches 71.25% balanced accuracy, while rejected samples are clustered into meaningful unknown-generator groups, obtaining an ARI of 0.81, an NMI of 0.90, and an overall clustering purity of 87.74%. In the incremental setting, the discovered generator space is progressively extended while maintaining a final purity of 99.23%. Cross-dataset experiments suggest that the pipeline can operate beyond the original dataset distribution, although post-processing remains challenging.

Computer Vision & Image Generation7/8/2026

Context-Aware Slum Mapping in Sub-Saharan Africa Using Sentinel-1 Texture and Local Climate Zones

Accurate mapping of informal settlements remains a major challenge in Sub-Saharan African (SSA) cities because optical imagery often fails to distinguish Informal Settlements (defined here as LCZ 7) from spectrally similar formal Compact Low-Rise areas (LCZ 3). This study presents a context-aware, reproducible Optical-SAR framework that improves informal settlement delineation using Sentinel-2 spectral features and Sentinel-1 structural information within an adapted Local Climate Zone (LCZ) taxonomy. We implement a three-tier SAR integration strategy: calibrated backscatter, GLCM textures, and a physics-guided feature engineered to capture the high structural disorder and weak radar return characteristic of SSA informal settlements. Using reference data across Nairobi and Eldoret (Kenya), we evaluate performance via a stratified hold-out protocol and a season-aware ablation study. Results show that SAR textures provide the dominant performance gain for LCZ 7 detection. The Optical-SAR model achieves overall accuracy of 0.816 (dry) and 0.807 (wet), significantly outperforming the WUDAPT baseline (OA 0.704) and reducing the critical LCZ 3 - LCZ 7 confusion to 7%. Seasonal analysis indicates that while optical-only separability varies with phenology, SAR-derived textures stabilize informal settlement mapping across seasons. These findings demonstrate that the incorporation of SAR-derived features yields consistent improvements for urban morphology mapping in data-scarce environments across seasons and across the evaluated source cities, while cross-city transfer remains limited without local adaptation strategies.

Computer Vision & Image Generation7/8/2026

Learning to Unify Deformable Shape and Texture Representations for Cardiac Video Classification

Deformable shape representations have proven to be robust complements to texture features in cardiac image classification, offering geometric priors that are invariant to imaging artifacts and intensity variations. However, existing deep networks perform simple concatenation to combine these distinct feature representations, which neither fully exploits their complementary nature nor learns cross-modal feature dependencies. Furthermore, this results in uniform attention across all timepoints; hence ignoring the varying diagnostic importance across the cardiac phases. In this paper, we propose a novel cardiac video classification model that, for the first time, learns temporal features in an integrated space of deformable shape and image texture representations. In particular, we design a bi-directional cross-attention in the latent space to fuse latent deformable shape and image features, allowing each modality to adaptively weight the other based on spatio-temporal correspondence. In contrast to current methods that apply uniform weighting across all the cardiac phases, our approach learns to dynamically adjust the contributions of shape and texture representations, derived from images, over time. We demonstrate state-of-the-art classification performance on a cine cardiac magnetic resonance (CMR) video dataset, achieving improved interpretability from attention mechanisms that identify diagnostically critical cardiac phases and modality contributions.

Computer Vision & Image Generation7/8/2026

Discovering Geometric Biases in 3D Face Reconstruction: A Curvature-Aware Spectral Framework for Fairness Evaluation

3D Morphable Models (3DMMs) remain the standard parametric shape priors for many state-of-the-art 3D face reconstruction algorithms. However, as these models are derived from a finite number of 3D face samples, they inherit the morphological biases of their training data, potentially limiting their generalizability across diverse global populations. In this paper, we propose a novel framework to analyze 3DMM reconstructions through the lens of surface curvature, with the objective to discover, quantify and visualize biases. While standard evaluation metrics often rely on Euclidean distances, our reconstruction error captures subtle surface nuances such as local topology or undulations. To do so, we leverage the Laplace-Beltrami Operator (LBO) to generate high-resolution curvature error maps, providing a localized and geometrically meaningful visualization of discrepancies between ground truth faces and reconstructed meshes. We derive from it an error metric that we validated through a user study, observing a significantly higher correlation to human perception compared to traditional methods. Furthermore, we conduct extensive experiments across several 3DMM bases and fitting algorithms, uncovering systematic age-related biases and providing preliminary evidence of biases associated with gender and ethnicity. Our findings highlight the necessity of adopting curvature-aware evaluation protocols to ensure demographic fairness and geometric precision in future 3D face reconstruction research.